Motor neuropathy usually starts in the hands and feet, and can affect the full extension of fingers and toes. In addition to the dexterity problems this obviously causes, it often also has a visual appearance of “clawlike” fingers. The condition is degenerative, getting worse over a period of months and years. Twitching and spasms can also happen in affected limbs. While motor issues associated with peripheral neuropathy usually accompany pain, tingling, and numbness, multifocal motor neuropathy involves no pain (only the motor nerves are affected). Generally, none of the varieties of motor neuropathy are life-threatening, although they can absolutely impact your comfort and quality of life if you suffer from them.